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Targeted Tumor Therapy with HIFU (High Intensity Focused Ultrasound) and TSLs (Temperature-Sensitive Liposomes) without changing the life quality of the patient…

The method of delivering doxorubicin, chemotherapy agent encapsulated within temperature-sensitive liposomes (TSLs) to tumor sites is opening a new era…

Liposomes are small lipid structures which can be used to encapsulate and deliver drugs through the bloodstream. Liposomal doxorubicin formulations have been available for a while. The nano-particle liposomes are injected into the bloodstream and can release their drug payload if exposed to small temperature elevations above body temperature. This permits for highly localized release of the drug at the tumor site, which could enhance the drug effectiveness and reduce side-effects.

A high intensity focused ultrasound (HIFU) system or Hyperthermia devices are used to heat the targeted area and activate the release of doxorubicin from the liposome. The studies have been shown to deliver 25 times more doxorubicin into tumors than does intravenous (IV) infusion alone, and 5 times more doxorubicin than standard liposomal formulations of the drug.
The goal is to expand the effective treatment zone in order to capture micro metastases, which are most commonly responsible for post treatment disease recurrence.
An early access program (EAP) is available for Hepatocellular Carcinoma (HCC) and Recurrent Chest Wall (RCW) Breast Cancer in the European Union, Switzerland, Turkey and Israel in the centers where superficial hyperthermia devices are used for     Temperature-Sensitive liposomal doxorubicin; please ask your doctor…
You can reach the details of HIFU system from the following page; http://www.en.meteks.com.tr/urun-detay/55/haifu

Tarih : 2.1.2017
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